p-TAU127 Alzheimer’s Test
The p-TAU127 Test
The p-TAU127 Test
This groundbreaking Alzheimer’s Assessment measures plasma p-Tau217, a specific protein identified as a reliable biomarker to aid in diagnosing Alzheimer’s disease (AD).1 This assay helps detect AD pathology, including extracellular amyloid-beta plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau (p-tau), before the onset of clinical symptoms.
Who should test?
The Alzheimer’s Assessment is intended for adult patients aged 45 and older who present with cognitive impairment and are being evaluated for AD or other causes of cognitive decline.
There are comorbid conditions that may affect phosphorylated tau levels in the blood. These can include conditions affecting hepatic and renal function, such as chronic kidney disease (CKD), as well as a history of stroke or myocardial infarction. Certain medications to support kidney function may also play a role in heightened levels of p-Tau217. Additionally, differences in results based on racial and ethnic background, sex, and age have not yet been established.
References
- Ashton NJ, Brum WS, Di Molfetta G, et al. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology. JAMA Neurol. 2024;81(3):255-263.
Convenient and Cost-Effective
A simple blood draw makes testing more accessible and cost-effective compared to lumbar puncture or imaging studies.
Highly Accurate Results
p-Tau217 shows a strong correlation with PET imaging and cerebrospinal fluid (CSF) testing, ensuring highly accurate results.
Early detection is key to preventing progression of this disease. Two studies found that levels of a protein called ptau217 in the blood were associated with damage to the brain caused by Alzheimer’s disease.
Blood tests identifying the protein help to diagnose the disease before symptoms develop.
Our Approach to the p-Tau127 test
We combine p-TAI-127 testing with our specialist support services. Initial consultations may take place in-clinic or over the telephone, to discuss your medical history and suitability for this test. Results are analysed and our specialist will tailor individual support for you that will equip you with the knowledge and tools to make necessary lifestyle changes aimed at improving your health for the future.
Have a question, want to know more or want to speak to us about this test?
Register your interest and we will contact you to discuss your needs.
Speak to a specialist adviser – 01423 313099
Alternatively to can click on the book now button below to book your consultation.
